Tietze Research Group
unveiling structure activity relationships of bioactive molecules
 

researcher ID D-4332-2012

ORCID  0000-0002-9251-1902

2023

40.  H. Abujubara, J. C. J. Hintzen, S. Rahimi, I. Mijakovic, D. Tietze, A. A. Tietze,* "Substrate-derived Sortase A Inhibitors: Targeting an Essential Virulence Factor of Gram-positive Pathogenic Bacteria.", 2023, Chem. Sci., DOI: 10.1039/D3SC01209C

39.   P. Bharmoria,* S. A. Ooi, A. Cellini, D. Tietze, M. Maj, K. Moth-Poulsen,* A. A. Tietze,* "Protein Cohabitation: Long-term Immunoglobulin G Storage at Room Temperature.", 2023, J. Mater. Chem. B, DOI: 10.1039/D3TB00161J

2021

38.    L. Montoliu-Gaya, D. Tietze, D. Kaminski, E. Mirgorodskaya, A. A. Tietze, F. H. Sterky*, "CA10 regulates neurexin heparan sulfate addition via a direct binding in the secretory pathway", 2021, EMBO Reportse51349, doi:10.15252/embr.202051349

37.      A. C. Baumruck, J. Yang, G.-F.  Thomas, L. I. Beyer, D. Tietze, A. A. Tietze*, "Native Chemical Ligation of Highly Hydrophobic Peptides in Ionic Liquid-Containing Media", 2021, J. Org. Chem.86 (2), 1659-1666


2020

36.      L. K. Müller, I. Duznovic, D. Tietze, W. Weber, M. Ali, V. Stein, W. Ensinger, A. A. Tietze, “Ultrasensitive and Selective Copper(II) Detection: Introducing a Bioinspired and Robust Sensor” 2020, Chem. Eur. J., 26 (39), 8511-8517 


2019


35.    D. Tietze, #* Desireé Kaufmann, # A. A. Tietze, A. Voll, R. Reher, G. König, F. Hausch, “Structural and dynamical basis of G protein inhibition by YM-254890 and FR900359: an inhibitor in action”, 2019, J. Chem. Inf. Model., doi:10.1021/acs.jcim.9b00433

34.      P. M. Wehrli, I. Uzelac, T. Olsson, T. Jacso, D. Tietze and J. Gottfries, “Discovery and development of substituted thiadiazoles as inhibitors of Staphylococcus aureus Sortase A”, 2019, Bioorg. Med. Chem., 27, 115043

33.   A. A. Paul George, P. Heimer, E. Leipold, T. Schmitz, D. Kaufmann, D. Tietze, S. H. Heinemann, and D. Imhof*, Effect of Conformational Diversity on the Bioactivity of µ-Conotoxin PIIIA Disulfide Isomers”, 2019, Marine Drugs, 17, 390

32.      D. Kaufmann, A. A. Tietze, D. Tietze*, “In Silico Analysis of the Subtype Selective Blockage of KCNA Ion Channels through the µ-Conotoxins PIIIA, SIIIA, and GIIIA”, 2019, Marine Drugs, 17, 180

31.      A. S. Kiryutin, G. Sauer, D. Tietze, M. Brodrecht, S. Knecht, A. V. Yurkovskaya, K. L. Ivanov, O. Avrutina, H. Kolmar and G. Buntkowsky*, "Ultrafast Single-Scan 2D-NMR Detection of a PHIP-Hyperpolarized Protease Inhibitor", 2019, Chem. Eur. J., doi:10.1002/chem.201900079

30.    D. Malfacini, J. Patt, S. Annala, K. Harpsøe, F. Eryilmaz, R. Reher, M. Crüsemann, W. Hanke, H. Zhang, D. Tietze, D. Gloriam, H. Bräuner-Osborne, K. Strømgaard, G. König, A. Inoue, J. Gomeza, and E. Kostenis*, "Rational design of a heterotrimeric G protein α subunit with artificial inhibitor sensitivity", 2019, J. Biol. Chem., doi:10.1074/jbc.RA118.007250


2018


29.      D. Tietze*, B. Koley-Seth, M. Brauser, A. A. Tietze, G. Buntkowsky*, “Ni(II)-complex formation and protonation states at the active-site of a nickel superoxide dismutase-derived metallopeptide: implications for the mechanism of superoxide degradation”, 2018, Chem. Eur. J., doi:10.1002/chem.201803042

28.     R. Reher, T. Kühl, S. Annala, T. Benkel, D. Kaufmann, B. Nubbemeyer, J. P. Odhiambo, P. Heimer, C. A. Bäuml, S. Kehraus, M. Cruesemann, E. Kostenis, D. Tietze*, G. König* and D. Imhof*, “Deciphering specificity determinants for FR900359-derived Gq alpha based on computational and structure-activity studies“, 2018, ChemMedChem, doi:10.1002/cmdc.201800304

27.     P. Heimer, A.A. Tietze, C. A. Bäuml, A. Resemann, F.J. Mayer, D. Suckau, O. Ohlenschläger, S. H. Heinemann, D. Tietze* and D. Imhof*, “Conformational peptide isomers revisited: The impact of disulfide connectivity on structure and bioactivity”, 2018, Anal. Chem., 90 (5), 3321-3327


2017


26.     A. C. Baumruck, D. Tietze, L. K. Steinacker, A. A. Tietze,* “Chemical synthesis of membrane proteins: a model study on the influenza virus B proton channel.” 2018, Chem. Sci., 9 (8), 2365-2375

25.     D. Tietze*, J. Sartorius,  B. Koley-Seth, K. Herr, P. Heimer, D. Imhof, D. Mollenhauer and G. Buntkowsky*, New insights into the mechanism of nickel superoxide degradation from studies of model peptides”, 2017, Sci. Rep., 7 (1), 17194

24.    A. C. Baumruck, D. Tietze, A. Stark and A. A. Tietze*, “Reactions of Sulfur-Containing Organic Compounds and Peptides in 1-Ethyl-3-methyl-imidazolium Acetate”, 2017, J. Org. Chem. 82(14), 7538-7545


2016


23.   J. K. Williams, D. Tietze, J. Wang, M. Lee, and M. Hong*, “Solid-State NMR Investigations of the Conformation, Proton Conduction, and Hydration of the Influenza B Virus M2 Transmembrane Proton Channel”, 2016, J. Am. Chem. Soc., 138, 8143-8155

22.   D. Tietze,# E. Leipold,# P. Heimer, M. Böhm, W. Winschel, D. Imhof, S. H. Heinemann, and A. A. Tietze*, “Molecular interaction of δ-conopeptide EVIA with voltage-gated Na + channels”, 2016, Biochim. Biophys. Acta, 1860 (9), 2053-2063

21.   A. T. Culbertson, A. A. Tietze, D. Tietze, Y. Chou, A. L. Smith, Z. T. Young, and O. A. Zabotina*, “A homology model of Xyloglucan Xylosyltransferase 2 reveals critical amino acids involved in substrate binding”, 2016, Glycobiology, 26, 961-972


2015


20.   Schrage, R.,# Schmitz, A. L.,# Gaffal, E.,# Annala, S., Kehraus, S., Wenzel, D., Bullesbach, K. M., Bald, T., Inoue, A., Shinjo, Y., Shridhar, N., Hesse, M., Grundmann, M., Merten, N., Charpentier, T. H., Martz, M., Butcher, A., Slodczyk, T.; Armando, S., Effern, M.; Namkung, Y., Jenkins, L., Horn, V., Stoßel, A., Dargatz, H., Tietze, D., Imhof, D., Gales, C., Drewke, C., Muller, C. E., Graeme, M., Tobin, A. B., Gomeza, J., Dohlman, H. G., Sondek, J., Harden, T. K., Bouvier, M., Laporte, S. A., Aoki, J., Fleischmann, B. K., Mohr, K., König, G. M., Tuting, T.,* Kostenis, E.*, “The analytical value of FR900359 to study Gq-regulated biological processes”, 2015, Nat. Commun., 6, 10156

19.   Liao, S. Y., Yang, Y., Tietze, D., and Hong, M.*, “The influenza m2 cytoplasmic tail changes the proton-exchange equilibria and the backbone conformation of the transmembrane histidine residue to facilitate proton conduction”, 2015, J. Am. Chem. Soc., 137, 6067-6077.

18.   Kwon, B., Tietze, D., White, P. B., Liao, S. Y., and Hong, M.*, “Chemical ligation of the influenza M2 protein for solid-state NMR characterization of the cytoplasmic domain”, 2015, Protein Sci., 24, 1087-1099


2014


17.   G. Sauer, D. Nasu, D. Tietze*, T. Gutmann, S. Englert, O. Avrutina, H. Kolmar*, G. Buntkowsky*, “Effective PHIP labeling of bioactive peptides boosts the intensity of the NMR signal”, 2014, Angew. Chem. Int. Edit., 53, 12941

16.   D. Tietze, S. Voigt, D. Mollenhauer, G. Buntkowsky*, “NMR-Crystallography as a novel Tool for the Understanding of the Mode of Action of Enyzmes: SOD a Case Study”, 2014, Appl. Magn. Reson., 1-17

15.   A-L. Schmitz, R. Schrage, E. Gaffal, T. H. Charpentier, J. Wiest, G. Hiltensperger, J. Morschel, S. Hennen, D. Häußler, V. Horn, D. Wenzel, M. Grundmann, K. M. Büllesbach, R. Schröder, H. H. Brewitz, J. Schmidt, J. Gomeza, C. Galés, B. K. Fleischmann, T. Tüting, D. Imhof, D. Tietze, M. Gütschow, U. Holzgrabe, J. Sondek, T. K. Harden, K. Mohr, E. Kostenis*, “A new mechanism to interdict heterotrimeric Gαq protein function with small molecules: “trapping” Gαq in the empty pocket conformation”, 2014, Chem. Biol., 21, 890-902


2013


14.   J. K. Williams, D. Tietze, J. Wang, Y. Wu, W. F. Degrado, and M. Hong*, “Drug-Induced Conformational and Dynamical Changes of the S31N Mutant of the Influenza M2 Proton Channel Investigated by Solid-State NMR”, 2013, J. Am. Chem. Soc., 135, 9885-9897

13.   M. Körner, G. Sauer, A. Heil, D. Nasu, M. Empting, D. Tietze, S. Voigt, H. Weidler, T. Gutmann, O. Avrutina, H. Kolmar, T. Ratajczyk, G. Buntkowsky*, “PHIP-label: parahydrogen-induced polarization in propargylglycine-containing synthetic oligopeptides”, 2013, Chem Commun (Camb), 49, 7839-7841

12.   A. A. Tietze, D. Tietze, O. Ohlenschläger, F. Ullrich, E. Leipold, S. H. Heinemann, and D. Imhof*, “Structurally diverse isomers of a pharmaceutically interesting µ–conotoxin”, 2013, Biopolymers, 100, 260-261, conference abstract

11.   S. Macholl, D. Tietze, G. Buntkowsky*, “NMR crystallography of amides, peptides and protein–ligand complexes”, 2013, Cryst Eng Comm, 15, 8627


2012


10.   M. Tischler, D. Nasu, M. Empting, S. Schmelz, D. W. Heinz, P. Rottmann, H. Kolmar, G. Buntkowsky*, D. Tietze* and O. Avrutina*, “Braces for the peptide backbone: Insights into structure-activity relationships of protease inhibitor mimics with locked amide conformations”, 2012, Angew. Chem. Int. Edit., 51(15), 3708-371

9.     A. A. Tietze, D. Tietze, O. Ohlenschläger, E. Leipold, F. Ullrich, A. Mischo, G. Buntkowsky, M. Görlach, S. H. Heinemann, D. Imhof*, “The one and only fold? Structurally diverse µ-conotoxin PIIIA isomers block sodium channel NaV1.4”, 2012, Angew. Chem. Int. Edit., 51(17), 4058-4061


2011


8.    D. Tietze, S. Voigt, D. Mollenhauer, M. Tischler, D. Imhof, T. Gutmann, L. González, O. Ohlenschläger, H. Breitzke, M. Görlach and G. Buntkowsky*, “Revealing the position of the substrate in NiSOD: a model study”, 2011, Angew. Chem. Int. Edit., 50(13), 2946-2950

7.    J. A. Frydel, M. Krzystyniak, D. Pienkowski, M. Pietrzak, N. de Sousa Amadeu, T. Ratajczyk, K. Idzik, T. Gutmann, D. Tietze, S. Voigt, A. Fenn, H.-H. Limbach, G. Buntkowsky*, “Efficient design of multituned transmission line NMR probes: the electrical engineering approach”, 2011, Solid State NMR, 39, 72-80


2010


6.   D. Tietze, M. Tischler, S. Voigt, D. Imhof, O. Ohlenschläger, M. Görlach, G. Buntkowsky*, “Development of a functional cis prolyl bond biomimetic and mechanistic implications for nickel superoxide dismutase”, 2010, Chem. Eur. J., 16(25), 7572-7578

5.   A. A. Miloslavina, C. Ebert, D. Tietze, O. Ohlenschläger, C. Englert, M. Görlach, D. Imhof*, “An unusual peptide from Conus villepinii: synthesis, solution structure, and cardioactivity", 2010, Peptides, 31(7), 1292-1300


2009


4.   D. Tietze, H. Breitzke, D. Imhof, E. Kothe, J. Weston, G. Buntkowsky*, “New insight into the mode of action of nickel superoxide dismutase by investigating metallopeptide substrate models”, 2009, Chem. Eur. J., 15, 517-523


2008


3.   G. Buntkowsky*, H. –H. Limbach, B. Walaszek, A. Adamczyk, Y. Xu, H. Breitzke, A. Schweitzer, T. Gutmann, M. Wächtler, J. Frydel, Th. Emmler, N. Amadeu, D. Tietze, B. Chaudret, “Mechanisms of dipolar ortho-/para-H 2O Conversion in Ice”, 2008, Z. Phys. Chem., 222, 1049-1063


2007


2.   S. Meyer, D. Tietze, S. Rau, B. Schäfer, G. Kreisel*, “Photosensitized oxidation of citronellol in microreactors”, 2007, J. Photochem. Photobiol., A, 186, 248-253

1.   G. Kreisel*, S. Meyer, D. Tietze, T. Fidler, R. Gorges, A. Kirsch, B. Schäfer, S. Rau, “Luminous diodes in chemistry - A union of various technologies”, 2007, Chem. Eng. Technol., 79, 153