Tietze Research Group
unveiling structure activity relationships of bioactive molecules
 















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researcher ID D-4332-2012

ORCID  0000-0002-9251-1902


Curriculum Vitae

Education:


10/2009

PhD defense, summa cum laude


11/2005 – 10/2009

PhD in chemistry, Friedrich-Schiller-University, Jena, Germany,

Prof. Dr. G. Buntkowsky (now Darmstadt University of Technology)

Title:Investigations on the Mechanism of Nickel Superoxide Dismutase Using Peptide Based Model Systems”


10/2004 – 08/2005

Diploma in chemistry, grade: excellent, Technical Chemistry and Environmental Chemistry, Friedrich-Schiller-  University Jena, Germany, Prof. Dr. G. Kreisel, Dr. S. Meyer

Title: Photooxidation von Citronellol in verschiedenen Reaktortypen“

(„Photo-oxidation of citronellol in various reactor types“) 


Professional Experience


06/2019 – current

Senior researcher, Department of Chemistry & Molecular Biology, Wallenberg Centre for Molecular and Translational Medicine, University of Gothenburg


01/2016 – 05/2019

Independent research group leader, Eduard-Zintl-Institute for Inorganic and Physical Chemistry, TU Darmstadt, Darmstadt, Germany

topics: structure, function and dynamics of small peptides and proteins in solution studied by NMR; pharmacophore-based, rational design of novel, peptidic Gprotein inhibitors


11/2016 – 01/2018

parental leave (part-time employment)


08/2013 – 12/2015

Senior scientist (independent junior researcher group leader), Eduard-Zintl-Institute for Inorganic and Physical Chemistry, TU Darmstadt, Prof. Dr. Gerd Buntkowsky

topics: structure activity relationship studies of ion-channel modifying cone snail toxins by NMR, in-silico design and analysis of G protein inhibitors


09/2015

Visiting scientist, National High Magnetic Field Lab (NHMFL), Tallahassee, FL, USA

topic: high-field EPR measurements of Nickel superoxide dismutase-derived Ni(II) metallopeptides


07/2012 – 07/2013

Visiting scientist (PostDoc), Department of Chemistry, Iowa State University, Ames, USA, Prof. Dr. M. Hong (now Massachusetts Institute of Technology - MIT, Cambridge, MA, USA)

topics: dynamics and conformation of the influenza proton channel studied by solid-state NMR; synthesis of membrane proteins


11/2009 – 06/2012

PostDoc, Eduard-Zintl-Institute for Inorganic and Physical Chemistry, TU Darmstadt, Prof. Dr. Gerd Buntkowsky

topic: 1,4- and 1,5-triazols as cis-amide bond mimics, solution NMR structure determination of conesnail toxins